Vamsi Mootha: Taking an inventory of mitochondria

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Vamsi Mootha: Taking an inventory of mitochondria

Mitochondria, the energy reactors of the cell, are estimated to contain approximately 1,500 proteins, but the mito-chondrial genome itself only encodes about 13 of them. The remaining proteins are immigrants that are encoded by the nuclear genome. Vamsi Mootha is using an integrative genomics approach to identify all of these proteins and their functions and to understand how their mutated vers...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 2008

ISSN: 1540-9538,0022-1007

DOI: 10.1084/jem.2056pi